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Automated pipelines for reproducible omics workflows

Containerized, scalable workflows built with Nextflow, Docker, and industry-standard bioinformatics tools. Select your analysis type to get started.

See the workflow
Live
Workflow builder WGS · germline

Reproducible by construction

Every Floxgen pipeline is a versioned, containerized Nextflow workflow. Pin a release and you get bit-for-bit identical results across laptops, on-prem clusters and the cloud — no "works on my machine," no dependency drift.

Containerized

Docker / Singularity images per process — fully isolated, fully reproducible.

Scalable

From a single sample to population scale — the same workflow, auto-parallelised.

Validated tools

BWA-MEM2, GATK, DeepVariant, STAR, VEP — industry standards, benchmarked.

API-driven

Trigger runs, stream logs and pull results over a clean REST API.

Stack & tools

Open-source, benchmarked components orchestrated by Nextflow and packaged in Docker.

Nextflow
orchestration
Docker
containers
BWA-MEM2
alignment
GATK4
variant calling
DeepVariant
ML calling
STAR / Salmon
RNA-seq
VEP
annotation
MultiQC
reporting

Run it

Launch any pipeline with a single command, or call the API from your own systems.

# launch the WGS germline pipeline
nextflow run floxgen/wgs-germline -r v2.4.1 \
  --input samples.csv --genome GRCh38 \
  -profile docker,cluster --outdir results/

Outputs

Every run emits analysis-ready artifacts plus a full provenance record.

Annotated VCF / gVCF

VEP-annotated calls, ready for the Aggregator and interpretation.

QC report

Interactive MultiQC across every sample and step.

Alignment metrics

Coverage, duplication and contamination summaries.

Provenance manifest

Versions, parameters and checksums for full reproducibility.